The fatal dose is estimated to be about 10-14 grams that's 150-200 mg of caffeine per kilogram of body weight. Very high doses of caffeine can cause death. Taking cola nut by mouth in very large doses is LIKELY UNSAFE due to its caffeine content. Stopping the use of caffeine suddenly can sometimes result in headaches, irritation, nervousness, anxiety, and dizziness. Also, due to its caffeine content, large amounts of cola nut might cause headache, anxiety, agitation, ringing in the ears, and irregular heartbeats. Chewing cola nut is associated with an increased risk of mouth cancer and gastrointestinal cancer. When cola nut is used medicinally in larger amounts or for a long period of time, it is POSSIBLY UNSAFE. The caffeine in cola nut can cause insomnia, nervousness and restlessness, stomach irritation, nausea and vomiting, increased heart rate and respiration, and other side effects. Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).Ĭola nut is LIKELY SAFE for most people when consumed in amounts found in foods.Ĭola nut is POSSIBLY SAFE when taken by mouth in medicinal amounts, short-term. More evidence is needed to rate the effectiveness of cola nut for these uses.

But this combination might not be appropriate for weight loss due to safety concerns related to ephedra.

Some early research, sponsored by a product manufacturer, suggests that taking cola nut in combination with ephedra and willow bark by mouth for up to 6 months might cause modest weight loss in overweight and obese people. Uses & Effectiveness Insufficient Evidence to Rate Effectiveness for.

Caffeinated nut